TLDR
- Cathie Wood’s ARK ETFs sold 21,592 Roku shares worth $2.12 million on September 25, 2025
- ARK also sold 10,667 Roblox shares valued at $1.42 million from the ARKK ETF
- The funds purchased 26,536 Arcturus Therapeutics shares worth $542,661 through the ARKG ETF
- Roku remains ARK’s third-largest holding with a 4.66% portfolio weighting despite recent sales
- Wall Street analysts rate Arcturus as “Strong Buy” with 198% upside potential over 12 months
Cathie Wood’s ARK Invest made three key portfolio moves on Thursday, September 25, 2025. The investment firm sold positions in streaming and gaming companies while adding to its biotech holdings.
The ARK Innovation ETF (ARKK) sold 21,592 shares of Roku Inc for $2.12 million. This represents the largest trade of the day for Wood’s flagship fund.
ARK also reduced its position in Roblox Corp, selling 10,667 shares worth $1.42 million. This follows an earlier sale of Roblox shares worth $2.71 million earlier in the week.
The trades come after strong performance from both companies this year. Roku has gained nearly 32% in 2025, while Roblox has surged 128%.
Despite the recent sales, Roku remains a key holding for ARK. The streaming platform company now ranks as the third-largest position across ARK’s combined portfolios with a 4.66% weighting.
Wood has been consistently reducing ARK’s Roku holdings over the past week. The pattern suggests a strategic decision to take profits after the stock’s strong run.
ARK Adds to Biotech Position
On the buying side, ARK’s Genomic Revolution ETF (ARKG) purchased 26,536 shares of Arcturus Therapeutics Holdings Inc. The biotech purchase was valued at $542,661.

This marks a continuation of ARK’s recent accumulation in Arcturus shares. The fund has been actively buying the biotech stock over several trading sessions.
Wall Street analysts currently rate Arcturus as a “Strong Buy” with consensus price targets. The average analyst price target suggests 198% upside potential for the stock over the next 12 months.
The biotech company focuses on RNA medicines and vaccine technologies. ARK’s increased investment reflects confidence in the company’s growth prospects.
Trading Pattern Reflects Strategy Shift
The trades represent smaller dollar amounts compared to Wood’s typical portfolio moves. This cautious approach comes during a period of increased market volatility, particularly in technology stocks.
Wood appears to be reallocating capital from consumer-focused tech companies toward sectors with perceived higher growth potential. These include biotechnology, artificial intelligence, and cryptocurrency-related investments.
The September 25 trades show ARK continuing to adjust its portfolio composition. The fund management team regularly rebalances holdings based on their forward-looking investment thesis.
ARK’s daily trading reports provide transparency into one of the most watched investment strategies in the market. Wood’s focus on disruptive innovation drives the fund’s active management approach.
The latest portfolio adjustments occurred on September 25, 2025, according to the funds’ daily disclosure reports.
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